Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephalitis.

Steiner J¹, Walter M, Glanz W, Sarnyai Z, Bernstein HG, Vielhaber S, Kästner A, Skalej M, Jordan W, Schiltz K, Klingbeil C, Wandinger KP, Bogerts B, Stoecker W.

Autoantibodies angainst glutamate receptors are found in a high percentage of patients diagnosed with schizoprenia, especially in first diagnoses. They could contribute or even cause many symptoms in at least a part of all schizophrenia cases. Hoewever, it is currently not common practice yet, to assess the presence of those antibodies in all first diagnosis cases of schizophrenia.

Dr. Moritz Muehlbacher

Psychiater

Glutamate-receptor autoantibodies in Schizophrenia

Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephalitis.